Here is a summary of multiomics data in the human and mouse germline cycle collected in GLEANER. Each row represents the type of multiomics data, including gene expression, DNA methylation, chromatin accessibility, and histone modification characteristics H3K4me3, H3K27me3 and H3K9me3. Each column represents the developmental stage of the germline cycle, which contains three major phases: preimplantation embryogenesis (blue), PGC development of postimplantation embryos (brown) and gametogenesis of after-birth individuals (orange). Numbers of table cells represent the sample number of each data type at each stage in the germline cycle. By clicking each cell of the table, the sample information which includes: data type, development stage, sample name, GSE&GSM accession number, and related citation’s title&PMID will be displayed under the table.

The integrative data matrixes of different data types are downloadable at the following links:


Zygote

2-cell

4-cell

8-cell

Morula

Epiblast

PGC(before 15w)

PGC(after 15w)

Oocyte(meiosis)

Pro-spermatogonia

Spermatogonia

Spermatocyte

Spermtid

Sperm

Oocyte

Gene Gene expression 22 27 41 78 88 8 213 156 650 12 12 6 73
DNA methylation 67 25 33 60 75 2 21 9 52 81
Chromatin accessibility 1 2 3 2 2 14 5 2 4 6
H3K4me3 1 1 2 3 2 1 4 4 1 4
H3K27me3 1 2 2 1 4 4 1 2
H3K9me3 2

Zygote

2-cell

4-cell

8-cell

Morula

Epiblast

E11.5 PGC

E12.5 PGC

E13.5 PGC

E14.5 PGC

Oocyte(meiosis)

Pro-spermatogonia

Spermatogonia

Spermatocyte

Spermtid

Sperm

Oocyte

Gene Gene expression 33 79 62 31 23 10 8 6 11 6 6 7 1 23 72
DNA methylation 22 31 27 37 23 3 4 4 6 16 2
Chromatin accessibility 2 6 4 4 2 3 4 4 4 8 4
H3K4me3 5 8 5 5 3 2 4 4 6 4 11
H3K27me3 5 6 3 4 2 3 4 4 8 1 6 8
H3K9me3 2 2 2 2 2 2 4 2